Genetics pathogenesis in the ovarian insufficiency
نویسندگان
چکیده
Premature Ovarian Failure (POF) is a heterogeneous syndrome characterized by Hypergonadotropic. Hypogonadism that affects about 1% of women younger than 40 years old, while an incidence of 1/1000 is reported in women younger than 30 years old [1]. This hormonal disorder is caused by the loss of the ovarian response towards the pituitary gonadrotropins synthesis (FSH and LH) that are secreted according to the inhibitory feedback between hypothalamus, pituitary gland and gonads.
منابع مشابه
The Genetics of Non-Syndromic Primary Ovarian Insufficiency: A Systematic Review
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Primary ovarian insufficiency (POI) can be a devastating disease impacting women below the age of forty. This involves a major decrease in the amount and quality of oocytes, or ovarian reserve in a woman. The distribution of single-nucleotide polymorphisms, rs10407022 and rs3741664, in Iraqi people and its association with primary ovarian insufficiency is the main objective of this study. The m...
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